Economic Policy in a New World Order
- Chair: Prof. Dr. Michael Müller
- Welcome address by Prof. Dr. Lutz Hein

Sustainability as a Challenge for the Pharmaceutical Sciences

From Phamaceuticals in the Environment to Greener Pharmacy and more Sustainable Pharmacy
- Chairs: Prof. Dr. Dagmar Fischer, Prof. Dr. Peter Langguth

Sustainable Strategies to contain antimicrobial resistance
- Chairs: Dr. Gesche Först, Prof. Dr. Anna Hirsch

11:00 Dr. Alexandra Weber (München)
Penicillin allergy delabeling

11:30 Prof. Dr. Alexander Harms (Zürich)
Viruses against superbugs: Bacteriophage therapy from bedside to bench and back

12:00 Dr. Adrian Richter (Halle)
Synthesis and Characterization of RNA Polymerase and ATP Synthase Inhibitors with Activity Against Resistant Mycobacteria

12:15 Nicole Zimmermann (Berlin)
Regrowth dynamics play an important role for the antibacterial effect of fosfomycin and amikacin in mono- and combination therapy against Escherichia coli

Chair: Dr. Laurine Kaul

List of Flash Talks

Novel strategies in nucleic acid therapeutics: genome editing and beyond
- Chairs: Prof. Dr. Achim Aigner

11:00 Prof. Dr. Toni Cathomen (Freiburg)
From Gene to Market: Genome Editing as a Therapeutic Reality

11:25 Prof. Dr. Zoltán Ivics (Leipzig)
Genetic engineering of therapeutic cells: Challenges and Solutions

11:50 Prof. Dr. Satoshi Obika (Osaka, Japan)
Development of nucleic acid derivatives for application in oligonucleotide therapeutics

12:15 Tristan Dewald (Mainz)
Development of RNA-based PROTACs as a strategy for targeting RNA-modifying enzymes

Chemical Epigenetics
- Chairs: Prof. Dr. Cristina Nevado, Prof. Dr. Manfred Jung

11:00 Dr. Martin Schröder (Basel)
Expanding the ligase and target space of targeted protein degradation

11:25 Prof. Dr. Wolfgang Sippl (Halle)
Structure based development of subtype selective histone deacetylase inhibitors for oncological diseases

11:45 Nicolas Heller, Prof. Dr. Manfred Jung (Freiburg)
Structure-based Development and Synthesis of Lysine Methyltransferase Inhibitors

12:00 Dr. Katherine Gosselé, Prof. Dr. Cristina Nevado (Zürich)
BAZ2A/B….the journey towards selective degraders

12:15 Dr. Christian Steinebach (Bonn)
Leveraging induced proximity modalities for drugging epigenetic proteins

Careers in Pharma: From Campus to Industry or Health Authorities
Get insights from early carreer professionals and experienced pharma leaders - and join the conversation

- Moderators: Dr. Reinhold Rößler

Expert Panel:
Federica Albissola, Regulatory Affairs Consultant
Dr. Sarah David, Novartis AG
Prof. Dr. Werner Knöss, Federal Institute for Drugs and Medical Devices (BfArM)
Dr. Jörg Schlingemann , Merck Healthcare KGaA
Dr. Hendrik von Büren , Retired Managing Director R&D, AbbVie

Rethinking antivirals
- Chairs: Prof. Dr. Christian Klein, Prof. Dr. Wibke Diederich

14:00 Prof. Dr. Arnold Grünweller (Marburg)
Being prepared - Targeting the host factor eIF4A as a pan-antiviral therapeutic strategy

14:25 Prof. Dr. Anna Hirsch (Saarbrücken)
Multiparameter optimisation of novel respiratory syncytial virus inhibitors targeting the F-protein

14:50 Dr. Christopher Veeck (Marburg)
Rethinking Antiviral Therapy: Exploring Targeted Protein Degradation as a Novel Antiviral Strategy

15:15 Dr. Thanigaimalai Pillaiyar (Tübingen)
Efficacy and structural insights of covalent dipeptide inhibitors on drug-resistant SARS-CoV-2 Mpro mutants

Natural products from plants, fungi and microorganisms
- Chairs: Prof. Dr. Andreas Bechthold, Prof. Dr. Gunhild Layer 

14:00 Prof. Dr. Simone Moser (Innsbruck)
From waste to value - exploiting plant senescence for natural products research

14:30 Prof. Dr. Ludger Beerhues (Braunschweig)
Biotechnology of hyperforin-like natural products for drug development

15:00 Prof. Dr. Silja Mordhorst (Tübingen)
Exploring bacterial natural products as a source of novel bioactive compounds

15:15 Dr. Karin Bartel (München)
Endolysosomal ion channels TPC2 and TRPML1 as promising anti-cancer targets

Scope and limits of drug recovery from altar chemicals and the environment
- Moderators: Prof. Dr. Michael Müller, Dr. Karina Witte

14:00 Short Presentations
Prof. Dr. Markus Heinrich (Erlangen)
Practical Examples of Pharmaceutical Waste Processing 
Johanna Greinke (Freiburg)
PFAS/TFA Challenges: Risks and Solutions

14:30 Pub quiz

15:00 Interactive work in smaller groups

- Pharmaceutical & Medicinal Chemistry: Hörsaal Rundbau
- Industrial Pharmacy: Hörsaal Chemie
- Pharmacology and Toxicology: Hörsaal Otto-Krayer-Haus
- Drug Control & Pharmaceutical Analysis: PI - Seminarraum R 00 003a 
- Pharmaceutical Technology and Biopharmaceutics: PI - Seminarraum R 00 018 
- Clinical Pharmacy: PI - Seminarraum R 00 019/020
- Radiopharmacy: On Wednesday, directly after the Radiopharmacy session

Guided tour: 16.45-17.45, followed by free strolling

Targeting the “undruggable": An RNA binding protein connecting tumor cells and the tumor microenvironment
- Chairs: Prof. Dr. Gregor Fuhrmann,  Prof. Dr. Claudia Jessen-Trefzer

For DPhG-members only

New Research, New Researchers
- Chairs: Dr. Kerstin Hiesinger, Dr. Wenxin Felix Zhu

9:00 Wiebke Fiebiger (Halle)
A novel tool to investigate inflammation-driven carcinogenesis: Modeling colorectal carcinoma in thromboxane receptor-deficient mice

9:15 Bernadette Vallaster  (Regensburg)
Assessment of covalent warhead reactivity heading towards druggable small molecule Caspase-2 inhibitors

9:30 Jana Haegner (Braunschweig)
Affinity Capillary Electrophoresis (ACE) as a Label-Free Binding Assay for Membrane Proteins: Application on CXCR2

9:45 Clemens Woitaske-Proske (Kiel)
Concept for the implementation of an environmental information, classification and dissemination system in Germany (“Arzneimittelindex Umwelt”)

10:00 Prof. Dr. Radosław Nowak (Bonn)
Targeting oncogenic transcription factors with small molecules

Sustainable drug carriers – from biological nanoparticles to natural polymers
- Chairs: Prof. Dr. Dagmar Fischer, Prof. Dr. Gregor Fuhrmann

9:00 Prof. Dr. Dagmar Fischer (Erlangen)
Bacteria help to heal – Drug delivery systems from bacteria for inflammation and infection

9:30 Dr. Andrea Zendrini (Zürich, Brescia)
Engineered Red Blood Cells-derived Vesicles for Synergistic Chemotherapy

10:00 Maria Krabbes (Leipzig)
Development of lipoplex-loaded biopolymer films as a local nucleic acid delivering wound dressing

10:15 Veronika Grassl (Erlangen)
A Library of Green and Sustainable Solvents for the Preparation of PLGA Nanoparticles Containing the Lipophilic Drug 6BIGOE

Cellular mechanisms – from understanding diseases to the development of ATMPs
- Chairs: Prof. Dr. Martin Hug, Prof. Dr. Hanna Seidling

9:00 Prof. Dr. Julia Stingl (Heidelberg)
ATMPs – what’s new from a regulatory perspective

9:30 Prof. Dr. Itsuko ISHII (Chiba, Japan)
Acrolein-modified lipoproteins influence on development of atherosclerosis

10:00 Fenja Klima (Berlin)
Model-informed CAR-T sampling strategies for efficient and robust clinical study designs: Towards better understanding of cancer immunotherapies

10:15 Sandra Witta, Hamburg
Towards Model-Informed Precision Dosing of Busulfan: An External Model Evaluation

Pharmacy and Crime
- Chairs: Prof. Dr. Marcus Plehn, Prof. Dr. Axel Helmstädter

9:00 Dr. Helena Barop (Freiburg)
Aus der Drogerie in den Giftschrank und zurück: Die (Ent-)Kriminalisierung von Cannabis

10:00 Dr. Marcus Carrier (Berlin)
Toxic! Chemical Analyses and Poisoning Trials in the 19th Century

Harnessing Medicinal Chemistry for Sustainable New Drugs
- Chairs: Prof. Dr. Bernhard Wünsch, Prof. Dr. Stefan Laufer

Sustainability meets innovation: Radiopharmacy between environmental awareness and modern tumor diagnostics
- Chairs: Prof. Dr. Sarah Spreckelmeyer, Prof. Dr. Andreas Maurer 

14:00 Assoz. Prof. Mag. Dr. Verena Pichler (Wien)
Sustainability in pharmaceutical sciences: Green principles of radiopharmacy

14:25 PD Dr. Mark Bartholomä (Homburg)
Delayed PET Imaging of metastatic, castration-resistent prostate cancer using longer-lived radionuclides

14:50 Prof. Dr. Bernd Neumaier (Köln, Jülich)
Production and isolation of astatine-211 for clinical applications

15:15 Punita Bhardwaj (Berlin)
Synthesis and Biological Evaluation of [198Au]Auranofin and 198Au-radiolabeled precursors in comparison to their non-radioactive counterparts

GLP-1 receptor agonists - more than antidiabetic therapy
- Chairs: Prof. Dr. Martina Düfer, Prof. Dr. Moritz Bünemann

14:00 Dr. Ralf Jockers (Paris)
How to rescue natural GLP-1R variants associated with impaired glucose control and increased adiposity

14:30 Dr. Johannes Broichhagen (Berlin)
Chemical Biology Probes Targeting the GLP1 Receptor

15:00 Dr. Sabine Willems (Sweden)
A chemogenomic approach to target identification in a primary human MASH model

15:15 Dr. Jorge Duque Escobar (Lübeck)
CRIP1 and the NLRP3 Inflammasome: A Silent Regulator Linking Inflammation to Hypertension?

Applications of nucleic acids and the technologies beyond
- Chairs: Dr. Laurine Kaul, Prof. Dr. Thomas Winckler

14:00 Prof. Dr. Ulrich Lächelt (Wien)
Synthetic delivery systems for nucleic acids and CRISPR/Cas genome editing 

14:30 Dr. Benedikt Kirchner
Extracellular nucleic acids as diagnostic biomarkers

15:00 Dr. Philipp König (Bonn)
Tackling Resistance to PARP-Inhibitors in Ovarian Cancer: The Role of DNA Repair Pathways and the Extracellular Matrix

15:15 Julia Leisel (Erlangen)
Tailored Design of Guanidinium-Functionalized Methacrylamides for Gene Delivery by Controlling Their Hydrophilic / Hydrophobic Balance

Analytics, data, digitalization
- Chairs: Prof. Dr. Hermann Wätzig, Prof. Dr. Maria Kristina Parr

14:00 Prof. Dr. Oliver Koch (Münster)
AI in Pharmaceutical Sciences: Let's talk about data

14:30 Marlon Krompholz (Braunschweig)
AI-powered Peak Integration - Mastering quantitative analysis in separation sciences

15:00 Marius Amann (Freiburg)
Computational Protein Design Enables Stabilization and Biophysical Characterization of Plasmodium falciparum Drug Targets for Drug Discovery

15:15 Claudia Stärk (Bonn)
Development of a monograph draft for lipid excipients in lipid nanoparticles used in mRNA vaccines

Jointly organized with the Bundesverband der Pharmaziestudierenden in Deutschland (BPhD)

Promovieren - Wie, wo und warum?
- Moderator: Prof. Dr. Ulrich Jaehde
- BPhD: Christiane Donat und Anna Jonas

Members' meeting of the working group Radiopharmacy

From Fasting to Wasting: Molecular Checkpoints in Obesity and Cancer
- Chairs: Prof. Dr. Elke Oetjen, Prof. Dr. Norbert Klugbauer 

Highlights in GPCR and nuclear receptor research
- Chairs: Prof. Dr. Matthias Schiedel, Dr. Dorothée Weikert 

16:45 Prof. Dr. Steffen Pockes (Regensburg)
Discovery of GPR3 ligands by combined virtual and conformational biosensor-based screening

17:10 Dr. Dorothée Weikert (Erlangen-Nürnberg)
Unlocking bitter taste: Ligand recognition by the bitter taste receptor TAS2R14

17:35 Prof. Dr. Bernhard Wünsch (Münster)
Bridged piperidines and piperazines as conformationally restricted kappa-opioid receptor agonists

18:00 Dr. Pascal Heitel (Frankfurt)
Scaffold Hopping Provides Subtype-selective Liver X Receptor Beta Agonists

Antibody-drug conjugates (ADC) - Advances and potential in tumor therapy
- Chairs: Prof. Dr. Achim Aigner, Prof. Dr. Raphael Reuten

16:45 Prof. Dr. Achim Aigner (Leipzig)
Antibody Drug Conjugates (ADCs): From Mechanisms of Action to Challenges and Perspectives

17:10 Prof. Dr. Michael Quante (Freiburg)
Antibody Drug Conjugate (ADC): Precision Medicine for Gastrointestinal Tumors

17:35 Prof. Dr. Christian Hackenberger (Berlin)
P5-labeling for generating highly efficacious antibody-conjugates for cancer therapy 

18:00 Corinna Weiler (Bonn)
Active disruption of GPCR-G protein interaction at the interface with a small molecule

Innovative strategies in the industrial development and life cycle of complex drugs – technological, analytical, and regulatory aspects
Chair: Dr. Reinhold Rößler, Dr. Hendrik von Büren 

16:45 Dr. Joachim Herrmann (Karlsruhe)
Pharmaceutical innovations for Herbal Medicinal Products - Opportunities and limitations

17:15 Dr. Jörg Schlingemann (Darmstadt)
The Nitrosamine Saga

17:45 Prof. Dr. Werner Knöss (Bonn)
Pharmaceutical quality in development and life cycle of medicinal products – today´s requirements and future needs

Adaptation of drug therapy during hot seasons
- Moderator: Ingo Meyer
Limited number of participants, registration required!

16:45 Prof. Dr. Andreas Matzarakis (Freiburg)
Wann erfolgen Hitzewarnungen und warum ist das relevant für unsere Gesundheit? 

17:00 Ingo Meyer (Köln)
Das Projekt ADAPT-HEAT: Informationen zu hitzesensiblen Medikamenten bekannter machen

17:15 Fragerunde

17:25 Thementische
Wie muss eine CALOR-Liste gestaltet sein, damit sie in der Praxis angewendet wird?

17:50 Vorstellung der Thementische und Plenumsdiskussion

Registration required

Markthalle Freiburg
Kaiser-Joseph-Straße 237
79098 Freiburg im Breisgau

Sustainability in Pharmaceutical Analysis
- Chair: Prof. Dr. Maria Kristina Parr, Prof. Dr. Ann Van Schepdael

9:00 Prof. Dr. Ann Van Schepdael (Leuven)
Capillary electrophoresis as a sustainable analytical tool for drug discovery and development

9:25 Dr. Andreas Otto (Waldbronn)
Transparency and Awareness: Key Drivers of Sustainability in Laboratory Environments

9:50 Dr. Felix Bredendiek (Berlin)
Sustainability in practice: challenges and solutions in the nitrosamine testing procedure

10:15 Dr. Banaz Jalil (London)
Does climate change impact the phytochemical quality of medicinal and aromatic plants? A case study of Lavandula species products

Gastro-intestinal drug contents and drug product performance
- Chairs: Prof. Dr. Peter Langguth, Prof. Dr. Werner Weitschies

9:00 Dr. Mirko Koziolek (Ludwigshafen)
The composition of human intestinal fluids and its impact on oral drug delivery

9:25 Dr. Linus Großmann (Greifswald)
Real-time Magnetic Resonance Imaging: An Innovative Tool for Biopharmaceutical Research

9:50 Valentin Stahl (Mainz)
Determination of drug release from tablets in viscous media

10:15 Prof. Dr. Philipp Uhl (Heidelberg)
Tetraether lipids – unique lipids with diverse applicability for oral delivery of macromolecules

Pharmaceutical Sciences in Freiburg
- Chairs: Prof. Dr. Jennifer Andexer, Prof. Dr. Manfred Jung

9:00 Prof. Dr. Jennifer Andexer (Freiburg)
Pharmaceutical Sciences in Freiburg

9:15 Dr. Laurine Kaul (Freiburg)
Targeted Degradation on Demand: Advancing PROTAC Delivery via Nanotechnology

9:40 Dr. Nico Fessner (Freiburg)
First Aid Kit for Medicinal Chemists: Enzymatic late-stage Functionalisation of Natural Products

10:05 Dr. Gesche Först (Freiburg)
Data-Driven Antimicrobial Stewardship: Turning Insight into Impact

How to write a DFG grant application
- Moderation: Dr. Torsten Hotopp, Prof. Dr. Michaela Schulz-Siegmund

9:00-9:30: Dr. Torsten Hotopp (Bonn)

Presentations by Successful Applicants for DFG Funding:
- Prof. Dr. Christa E. Müller (Bonn)
- Prof. Dr. Miriam Breunig (Regensburg)

Discussion with the Speakers and Elected Members of the DFG Review Board (Prof. Dr. Stefan Laufer (Tübingen), Prof. Dr. Bernd Neumaier (Jülich, Köln) Prof. Dr. Michaela Schulz-Siegmund (Leipzig)).

Shaping the future of pharmacy with pharmacogenetics research and implementation
- Chairs: Dr. Gesche Först, Prof. Dr. Oliver Scherf-Clavel